DOI: 10.21276/sajp

Pages: 311-319

Today’s World Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances are combined to a pure drug substance to produce a final medicinal product. Formulation studies involve developing a preparation of the drug which is both stable and acceptable to the patient. For orally taken drugs, this usually involves incorporating the drug into a tablet or a capsule. It is important to appreciate that a tablet contains a variety of other substances apart from the drug itself, and studies have to be carried out to ensure that the drug is compatible with these other substances. In this present study to formulate the tablet form of commiphora mukul (guggil- 100) and evaluate the preformulation characterization of a guggil-100 physical, chemical, and mechanical properties are involed the other ingredients should be used for the preparation. Formulation studies then consider such factors as pH, moisture, disintegration, friability, dissolution, particle size, polymorphism and solubility, as all of these can influence bioavailability and hence the activity of a guggil-100. In addition that to evaluate the extractive values and microbial load on the guggil-100.