DOI: 10.36347/sjams.2018.v06i12.049

Pages: 4886-4897

Post-operative nausea and vomiting is one of the commonest & most unpleasant complaint following laparoscopic surgeries. It can lead to several emergencies like wound dehiscence, bleeding, aspiration of gastric contents, delayed hospital discharge, unexpected hospital admission and dissatisfaction among patients. This study is intended to compare the efficacy of ondansetron and dexamethasone alone and combinations of dexamethasone plus ondansetron in patients undergoing laparoscopic surgeries, with respect to nausea, vomiting and requirement of rescue anti-emetics. We studied 150patients between age group of 20yr to 50yr of ASA I & II requiring general anesthesia for laparoscopic surgeries, in a randomized clinical trial. 50 patients received 4mg ondansetron, intravenously and another 50 patients received dexamethasone 8mg intravenously and 50 patients received 4mg ondensetron+8mg dexamethasone 10min before induction, post operatively patients were assessed at time interval of 0-6hours and then at 6-24 hours for degree of nausea, vomiting and requirement of antiemetic drug.