DOI: 10.36347/sjams.2018.v06i12.051

Pages: 4906-4910

Tuberculosis (TB) is one of the major concerns of health policy and rapid detection of M. tuberculosis and detection of rifampicin (RIF) resistance in infected patients are essential for disease management. Multi-drug resistance (MDR) TB is defined as tuberculosis (TB) disease caused by a strain of Mycobacterium tuberculosis (MTB) that was resistant to at least isoniazid and rifampicin (RIF). The aim of this study was to evaluate the importance of GeneXpert MTB/RIF for detection of Mycobacterium tuberculosis (MTB) with detection of rifampicin (RIF) resistance. In this study 320suspected cases of pulmonary and extra-pulmonary TB were included. Their sputum and other (Pus, CSF, tissue, etc.,) samples were collected and subjected to smear microscopy test followed by GeneXpert MTB/RIF assay. Of total 320 suspected cases, Mycobacteria were detected in 152 patients (47.5%) by GeneXpert MTB/RIF and ZN stain.