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Scholars Academic Journal of Pharmacy | Volume-6 | Issue-08
Association between Serum Ferritin level and Non Alcoholic Fatty Liver Diseases in Khartoum Sudan
Waleed Mohamed Alameen Al-Zibair, Mariam Abbas Ibrahim, Abdelgaidr Eltom
Published: Aug. 26, 2017 |
290
109
DOI: 10.21276/sajp
Pages: 359-362
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Abstract
Non-alcoholic fatty liver disease (NAFLD) refers to the accumulation of hepatic steatosis not due to excess
alcohol consumption. It is the most common liver condition in the world. The prevalence of NAFLD is up to 30% in
developed countries and nearly 10% in developing nations. The aim of this study was to assess serum ferritin level
among Sudanese with non-alcoholic fatty liver disease. This was a case control study conducted in Advance diagnostic
center, Bahary hospital, Khartoum state, Sudan in April 2017. Participants were divided into two groups; patients with
non-alcoholic fatty liver disease (N/40), and 40 normal healthy individuals as control group. Serum Ferritin will was
measured by using automated enzyme immunoassay system (TOSOH). The study results revealed that there is a
significant difference in serum ferritin between cases and control group (P = 0.03). The study also showed moderate
positive correlation between ferritin and age (R = 0.412), (P = 0.00). Patients with NAFLD have higher serum ferritin
level than those without fatty liver changes. Serum ferritin levels rise as grade of liver steatosis increases.