DOI: 10.36347/sjams.2017.v05i06.015

Pages: 2100-2103

The involvement and role of serum uric acid as a risk factor for acute ischemic stroke is still controvertible. Evidences suggest that treatments with a hypo uraemic action have an effective role in cardiovascular risk prevention. In the present study association between serum uric acid and ischemic stroke was assessed. This hospital based case control analysis contain 50 acute ischemic stroke cases and age, sex matched 50 control subjects. Serum uric acid levels in the first 48 hours of admission were estimated with photometry method. The mean serum uric acid level in cases was 6.48 ± 1.92 mg/dl whereas it was 5.09±1.07 mg/dl in control subjects. The mean serum uric acid level was significantly higher in cases as compared to controls; this analysis shows that hypertension, smoking, and obesity were found to be independently associated with ischemic stroke. It was also found that serum uric acid was also independently associated with ischemic stroke. Elevated SUA is independently associated with acute ischemic stroke and significantly associated with hypertension, diabetes mellitus, smoking, obesity, metabolic syndrome and poor functional outcome after stroke.