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Scholars Journal of Applied Medical Sciences | Volume-5 | Issue-06
Levels of serum prolactin and estradiol hormone of pre-and postmenopausal women breast cancer in misan city –Iraq: Comparative study
Mohammed Abdul-Mounther, Ali Abdul Aziz Al-shawi, Hanaa S. Khadem, Mahdi M. Thuwaini
Published: June 30, 2017 | 282 208
DOI: 10.36347/sjams.2017.v05i06.027
Pages: 2175-2178
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Abstract
Most of epidemiologic studies were suggested that hormones concentration in blood are associated with breast cancer and because of limited comparative data about breast cancer concerning Iraq, This study was conducted whether prolactin and estradiol level were associated with weighting as risk factor. However, the analysis include 58 cases of breast cancer (10 patients of premenopausal and 48 patient of post-menopausal) and 30 healthy women as control (15premenopausal. and 15 postmenopausal), with similar age range (22-≤ 50 years) were assessed for prolactin, estradiol and BMI. The study was declared significant increase prolactin as well as BMI in premenopausal group (p<0.001). Conversely, estradiol was decreased with increase age in the postmenopausal phase in comparison to the control. These data were indicated to important the prolactin and estradiol in breast cancer etiology of patients of misan city, southern of Iraq.