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Scholars Academic Journal of Pharmacy | Volume-6 | Issue-09
Review on Sleep and Sleep Disorders
Sudha Chandra Burepalli, Priyanka Punuru, Gnaneswar Gottiganti, Jeevan Kumar Badhvel, Chakka Gopinath
Published: Sept. 30, 2017 |
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DOI: 10.21276/sajp.2017.6.9.1
Pages: 372-377
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Abstract
Sleep is a complex neurological state, with its primary function of providing
rest and restoring the body’s energy levels. Normal human sleep is divided into non–
rapid eye movement (NREM) and rapid eye movement (REM) sleep, and the alteration
between NREM and REM occurs about 4-5 times during a night of normal sleep. Human
NREM sleep could be classified into four stages, namely, stage I, II, III and IV,
representing successively deeper stages of sleep and rapid eye movement (REM) sleep
characterized by rapid eye movements, muscle atonia and desynchronized EEG.
Alterations in the quality, quantity and pattern of sleep result in sleep disorders. Though
there are more than 100 identified sleep/wake disorders, most sleep complaints can be
categorised into five, namely, hypersomnia, insomnia, circadian rhythm disorders,
parasomnias and sleep disorders associated with mental, neurological and other medical
disorders. Sleepiness during waking hours results from volitional or forced sleep
deprivation during previous nights due to social, economic and environmental reasons.
Daytime sleepiness, sleep deprivation, and irregular sleep schedules are highly prevalent
among college students, as 50% report daytime sleepiness and 70% attain insufficient
sleep. Sleep disorders diagnosed based on history and polysomnography findings.