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Scholars Academic Journal of Pharmacy | Volume-6 | Issue-10
Drug-Excipient Interaction Study of Lornoxicam with Polymers
Vaibhav Mhasal, Sumedh N. Moharil, Bhakti Mali, Mahesh B. Narkhede
Published: Oct. 30, 2017 |
238
346
DOI: 10.21276/sajp.2017.6.10.2
Pages: 423-428
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Abstract
Interaction study is the most important step in reformulation study for the
preparation of all dosage forms. The interaction can affect physical, chemical, therapeutic
and biological properties and stability of drug and create a new surprise problem, the
successful formulation of stable and effective solid dosage form depends on the careful
and suitable choice of excipient. Also the selection of excipient is vital in the design of a
quality drug product. The quality of medicine depends not only on the active principals
and productions process, but also on the performance of the excipients .The present work
shows the interaction study of Lornoxicam and polymers for Nano products. In IR the
interaction of infrared radiation with matter. It covers range of techniques, mostly based
on absorption spectroscopy. DSC is a thermo-analytical technique in which the difference
in the amount of heat required to increase the temperature of sample and reference is
measured as a function of temperature.