DOI: 10.21276/sajp.2017.6.12.1

Pages: 476-481

To explore the impact of different patient-specific factors on the daily warfarin maintenance dose. This is a cross sectional study which was conducted on 80 Iraqi patients of Arab ethnicity. The ethical approval of this study was obtained from the Medical College / Al-Nahrain University and conducted in accordance with the Declaration of Helsinki. After sample addition, tubes were transferred to the laboratory for PT&INR measuring. Demographics of gender, age, weight, and height, Body mass index (BMI) was calculated via weight and height as well as date of warfarin initiation, and indication, additional medical problems and concurrent medications were also recorded. Warfarin dose was not significantly correlated with gender and height, while it was significant with age but negatively correlated so as the age increased the dose decreased, and warfarin dose was highly significant with weight and body mass index and positively correlated so as the body weight increase warfarin dose increase. The target INR is highly not significant with dose. Simple linear regression equation showed a significant effect of age, height, weight, and BMI on daily warfarin maintenance dose with a no significant effect of gender.