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Scholars Academic Journal of Pharmacy | Volume-6 | Issue-12
Antibiotic Susceptibility Pattern of Bacterial Isolates from Surgical Site Infections in a Teaching Hospital, Tirupati, Andhra Pradesh
Chandrakala Penagadam, Shanmugam Yamanaboina, CH. Srinivasarao
Published: Dec. 30, 2017 |
218
96
DOI: 10.21276/sajp.2017.6.12.5
Pages: 511-518
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Abstract
Surgical site infection (SSI) is a severe problem in the surgical specialties,
which can cause mortality, morbidity, delays incision healing and economic burden.
Advances in control of infections have not completely eradicated this problem because of
development of drug resistance. Aims and objectives are isolation and identification of
the bacterial pathogens from the infection site and determine the antibiotic susceptibility
pattern of the isolated pathogens. A total number of 210 clinically suspected cases of
surgical site infections in various surgical departments during July 2009 to April 2010
were included. Standard bacteriological methods were used for bacterial isolation and
Susceptibiliity testing. Among enrolled cases the age of the patients ranged from ≤20 yrs
to ≥ 60 yrs. Out of 210 wound swabs 167/210 were culture positive aerobically yielding
235 bacterial isolates, while 43 were sterile. Of this 112/131 were emergency surgery
patients. The maximum rate of isolates was seen after EmLSCS. Of all risk factors preoperative stay of >7 days was considered as the most significant. All Gram positive cocci
isolated were sensitive to Vancomycin (100%), followed by Amikacin and Clindamycin.
81.16% of S.aureus were sensitive to Oxacillin.