DOI: 10.36347/sjmcr.2016.v04i08.004

Pages: 576-580

This is a case report of synovial sarcoma of left pyriform fossa in a 35 year old male who presents in ENT Department with complaints of foreign body senssation since two months and difficulty in swallowing solid foods since 1 month duration. A globular swelling was seen in left pyriform fossa on indirect laryngoscopy. A CECT neck confirmed a well defined localised mass of 2cm x 1.4cm. Excisional biopsy was taken on direct laryngoscopy. Histological diagnosis of biphasic synovial sarcoma was confirmed by immunohistochemistry and molecular analysis. Clinical follow up with CT 3 months after operation has not shown any residual disease and patient if on regular follow up. Synovial sarcoma is a rare malignant tumor. It derives from a mesenchymal precursor stem cell that is unrelated to mature synovial tissue. Synovial sarcoma classically affects lower limbs between the ages of 15 and 40 years and the proportion of male-to-female patients is 3:2. It is very rare in the head and neck region especially in laryngopharynx. We report a case of pyriform fossa synovial sarcoma confirmed by histopathology and immunohistochemistry. To the best of our knowledge this is the third case in India and first in Valley of Kashmir (Srinagar) documented in English Literature.