DOI: 10.36347/sjams.2023.v11i03.026

Pages: 633-638

Background: Perinatal asphyxia, or more accurately, hypoxic-ischemic encephalopathy (HIE), remains a devastating illness, producing considerable death and long-term morbidity despite great breakthroughs with sophisticated monitoring technologies and understanding of fetal and neonatal pathology. Objective: In this study our main goal is to evaluate the maternal risk factor for HIE progression in infants. Method: This case control study was conducted in the Department of the Paediatrics, Jalalabad Ragib Rabeya Medical College Hospital, Sylhet during the period from 1 st January 2014 to 30 th June 2014. Ninety-six normal birth weight term babies with HIE were selected as case; Ninety six sex and birth weight matched, term singleton baby without HIE born in Jalalabad Ragib Rabeya Medical College Hospital, Sylhet were taken as control. Results: Maternal age (<20 years) [15 (15.6%) versus 6 (6.2%); OR=3.165; 95% of CI=1.176-8.518; p=0.037]; maternal height (<145 cm) [37 (38.5%) versus 24 (25.0%); OR=1.881; 95% of CI=1.014-3.492; p=0.044), primiparity [45 (46.9%) versus 31 (32.3%); OR=1.850; 95% of CI=1.029-3.325; p=0.039], irregular or no antenatal care [41 (42.7%) versus 27 (28.1%); OR=1.905; 95% of CI=1.044-3.476; p=0.035]; pregnancy induced hypertension [38 (39.6%) versus 22 (22.9%);OR=2.204; 95% of CI=1.777-4.128; p=0.013]. Conclusion: Maternal risk factors of development of hypoxic ischemic encephalopathy are maternal age (& lt;20 years), primigravida mother, absence or irregular antenatal care, pregnancy induced hypertension is associated with HIE.