DOI: 10.36347/sjmcr.2016.v04i09.011

Pages: 666-667

Psoriasis is a chronic autoimmune disease which is characterized by scaly plaques over extensor surfaces of the body. Psoriasis is generally thought to be a genetic disease which is triggered by environmental factors including infections and psychological stress and genetic factors. Alcohol is found to be a risk factor for psoriasis as it enhances the production of inflammatory cytokines and cell cycle activators, such as cyclin D1 and Keratinocyte Growth Factor, which could lead to epidermal hyperproliferation. Alcohol misuse induces immune dysfunction resulting in psoriatic lesions exacerbation. Our case report shows increased risk of psoriasis with intake of alcohol.