DOI: 10.36347/sjmcr.2016.v04i10.002

Pages: 704-706

Anorectal melanoma is an uncommon and aggressive disease. We present one case of rectal malignant melanoma with history of chronic constipation in one Iranian man. In April 2015, a 73-year-old farmer man referred to Clinic of Surgery with complaints of abdominal pain and bloody stool since two months ago with history of chronic constipation. He did transanal rectal mass resection. The IHC report in May 2015, showed that Melan-A and HMB-45 were positive and synaptophysin and LCA were negative. Eight days later, he did abdomino perineal resection with pelvic lymph node dissection. A rectosigmoid sample with dimension 22.5*3.5 cm and thickness of 2cm with distance of 1.5cm from rectum’s margin was sent to pathobiology laboratory. Five days after surgery, the patient was ill with abdominal pain, tachypnea, respiratory distress and black necrotic malodorous site of colostomy. He died in June 2015 (five days after second surgery) due to cardiopulmonary arrest unresponsive to cardiopulmonary resuscitation. In conclusion, malignant rectal melanoma is aggressive malignancy and therefore, immediate and precise diagnosis is necessary. Also, due to rarity and misdiagnosis, physicians should be much more familiar with malignant melanoma and its clinical awareness.