DOI: 10.36347/sjmcr.2016.v04i12.001

Pages: 883-885

Bone and joint infection is the main complication of bone fracture as a result of pyogenic bacteria. The long-term clinical course, extended period of silence, cases of recurrence and abundant discharge are the overriding side effects of bone infection that can be considered a challenge to treat the patients. Given the associated problems of bone infection, the aim of current study is to elucidate the efficiency of Antibiotic loaded bone cement (ALBC) as the novel method to treatment of chronic osteomyelitis. This study looks at the treatment of chronic osteomyelitis through cement containing antibiotic approach. Five patients with chronic osteomyelitis as a consequence of surgical operation of bone fracture were evaluated for efficiency of ALBC method (Gentamicin and Vancomycin have been used as antibiotics in our homemade bone cement). The study was performed in Imam Khomeini hospital of Falavarjan in Isfahan between February 2009 to January 2014. The patient information was obtained from the hospital data bank to monitor treatment and recovery. The ALBC application in temporary manner leads to magnificent results about treatment of chronic osteomyelitis and septic arthritis. However, extensive and complete debridement of necrosis and infectious area with application of proper fixation and bone graft should be considered with the ALBC. Our results have shown that antibiotic loaded cement leads to reduction of pyrogenic discharge as the main clinical complication of chronic osteomyelitis in all patients also; the application of extensive debridement and antibiotic drugs is declined. It should be noted that the patient satisfaction was increased by this approach. Finally, the cement-containing antibiotic can be suitable approach to reduce bone infection.