DOI: 10.36347/sjmcr.2023.v11i03.040

Pages: 406-409

Serum amylase and lipase levels are commonly used as diagnostic markers for acute pancreatitis, but elevated levels of these enzymes can also occur in other conditions. We report a case of a 45-year-old male with a known history of type 2 diabetes who presented with nausea, vomiting, and abdominal pain. Laboratory investigations revealed hyperglycemia, ketonemia, metabolic acidosis, and elevated levels of serum amylase and lipase. However, imaging studies did not reveal any evidence of acute pancreatitis or other abdominal pathology. The patient was diagnosed with diabetic ketoacidosis and managed with fluid resuscitation, insulin therapy, and correction of metabolic acidosis. The serum amylase and lipase levels gradually normalized, supporting the diagnosis of diabetic ketoacidosis without complicated with acute pancreatitis. This case highlights the importance of considering alternative diagnoses in the setting of elevated serum amylase and lipase and appropriate management of diabetic complications to prevent the development of more severe conditions.