DOI: 10.36347/sjmcr.2017.v05i02.005

Pages: 81-84

Hemophagocytic lymphohistiocytosis is a defect in the immune response leading to hypercytokinemia and an unbridled activation of lymphocytes and histiocytes with a uniformly fatal outcome in absence of treatment. We evaluated a 1.5 month old female child, who presented with clinical features of sepsis, but soon developed pancytopenia and deranged coagulation profile. Radiological investigations showed hepatosplenomegaly and bone marrow revealed hemophagocytosis by histiocytes.