DOI: 10.36347/sjmcr.2017.v5i08.006

Pages: 473-474

Pain and painful events are the top complaints among reasons for referral to a physician. Analgesics and non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed drugs following antibiotics. In spite of all efforts and scientific steps, arthritis and drug use are challenging subjects for mistakes and their selection, with advanced approaches often changing. It may be useful to look over worldwide statistics in order to define the magnitude of the problem. For osteoarthritis and rheumatoid arthritis, which are common, the prevalence is 10-20% and 1-2%, respectively, and at least half of these patients use NSAID. The prevalence of NSAID usage in the community has been calculated as 5%. In this article, we present an 81-year-old patient who had a single dose of tenoxicam injection for osteoarthritis with subsequent deterioration of clinical and laboratory parameters. The patient's laboratory results were consistent with acute renal failure and liver failure. The patient, developed multiorgan failure despite the treatment, was considered exitus on the 6th day of the treatment. Clinicians should keep in mind that NSAIDs may have systemic toxic effects. Because, these drugs can cause mortality if not initiated early treatment.