DOI: 10.36347/sjmcr.2017.v05i09.002

Pages: 521-526

Papillary thyroid carcinoma (PTC) is the most common thyroid carcinoma accounting for 85 to 90% of all thyroid cancers, the incidence of which is increasing worldwide. PTC has many variants and one of them is well-differentiated follicular variant (FV-PTC) that represents about 20% of the all PTCs, generally have a good prognosis. Important features for diagnosing FV-PTC are the ground glass appearance, nuclear grooving and intranuclear pseudo-inclusions, with an exclusive or almost exclusive follicular pattern of growth arranged in a nodular structure. Herein we report a case of PTC- follicular variant occurring in 52 years old woman involving the entire thyroid gland and adjacent lymph nodes, which was previously diagnosed as multinodular goitre. Involvement of cervical lymph nodes is very common (particularly in young patients), and it may be the first manifestation of the disease. The nodal metastases have a tendency to undergo cystic changes.