DOI: 10.36347/sajp.2023.v12i04.001

Pages: 79-85

Nearly every facet of modern life has been profoundly impacted by the development of nanotechnology. Researchers from a variety of disciplinary domains are becoming interested in nanoparticles (NPs) with distinctive physicochemical features and broad medicinal uses. Because of their distinct structural characteristics, NPs have a wide range of uses in medication delivery, chemical and biological sensing, and other related fields. Oxidative processes are unavoidable as they are important in energy metabolism and the utilization of nutrients. The treatment available may not be sufficient to treat the disease as it is caused by many factors and there are so many adverse effects caused by the synthetic medicine available. The present study evaluated the phytochemical, phenolic, flavonoid, and antioxidant activity of Noni seed synthesized with silver nitrate. Fresh seeds of Morinda citrofolia obtained were extracted by maceration method and synthesis was done by reacting 10 mL of the Morinda citrofolia seed extract with 90 mL AgNO3 solution. Phytochemical, TPC, TFC, and antioxidant tests were carried out according to standard procedure. Results revealed that Noni seed AgNps contains alkaloids, tannins, flavonoids, resins, and terpenoids. Phenolic content was non-significantly different (p>0.05) and flavonoid content was significantly different (p<0.05) in comparison to gallic acid. Noni seed-AgNps extract also showed high antioxidant activity because of their higher percentage inhibitions very near to the controls used. From the study, we can conclude that Noni seed-AgNps extract has many important secondary metabolites and it has a potential for strong antioxidants.