DOI: 10.36347/sjmcr.2023.v11i05.024

Pages: 844-846

Acute Fatty Liver of Pregnancy (AFLP) is a rare but serious condition that can result in significant maternal and fetal morbidity and mortality. Although fetal extraction is currently the only curative treatment, advances in extrarenal purification techniques such as plasmapheresis have helped to significantly decrease associated mortality rates. However, in cases where major organ dysfunction is present with major hemodynamic instability, plasmapheresis alone may not be adequate or even detrimental, thus imposing alternative therapeutic options. In this report, we present a case study of a 51-year-old primiparous patient who was 34 weeks pregnant and developed AFLP complicated by postpartum hemorrhage, multi-organ failure, and hemodynamic instability. The patient was successfully treated with isolated continuous venovenous hemofiltration (CVVH) resulting in a favorable clinical outcome.