DOI: 10.36347/sjmcr.2018.v06i03.005

Pages: 133-135

The term metaplsia has traditionally been reserved for neoplasms that exhibit microscopic structural changes which diverge from glandular differentiation. In the breast, these phenotypic alterations represent the expression of genotypic properties not manifested in normal myoepithelial cells or glandular epithelial cells of the breast. Metaplastic breast carcinoma is a rare breast neoplasm with an incidence of 0-2.5%. This heterogenous group of tumors are characterised by an admixture of adenocarcinoma with dominant areas of spindle cells, squamous cells and/or mesenchymal differentiation.