DOI: 10.36347/sjmcr.2018.v06i03.012

Pages: 160-162

Systemic lupus erythematosus is a non-specific organ autoimmune disease characterized by clinical polymorphism and positive antinuclear antibodies. The aim of this study was to evaluate the presence of lymphadenopathies during lupus disease. It is a retrospective study of six (06) patients who are married, Malians and suffering from lupus disease. The study was carried out at the service of internal medicine of Military Hospital of Kati over a two (02) year period (from December 2015 to January 2017). The only criteria for inclusion were the presence of one or several lymphadenopathies without considering the size. Lymphadenopathies were found in three lupus patients among six (50% of patients); the mean age was 26, 33 years. Peripheral lymphadenopathies involved cervical area in one case (16, 66%), inguinal area in two cases (33, 34%). In all patients, all of the following exams were positive: anti-native DNA antibodies, anti-Sm antibodies, anti-Ro/SS-A antibodies and/or anti-La/SS-B and hypocomplementaemia. Development under Corticotherapy appeared to have a favorable effect with adenopathy regression in five patients. Only one case didn’t receive methotrexate and its lymphadenopathies regression were noticeable. Lymphadenopathies generally occur during lupus outbreak. However, an investigation for an etiology is necessary in order to eliminate possible infectious cause especially tuberculosis.