DOI: 10.36347/sjmcr.2018.v06i06.003

Pages: 376-378

Sjögren’s Syndrome is a common, chronic autoimmune disease that typically affects salivary and lacrimal glands. The immune response damages the exocrine glands and results in the typical symptoms of dry eye and dry mouth. There are other various systemic and focal symptoms, as well. Vasculitis is one of the most common extraglandular manifestations of the disease and skin vasculitis, and leukocytoclastic vasculitis is the most frequent ones. However, some studies revealed an acute necrotizing arteritis of medium-sized vessels similar to polyarteritis nodosa may be seen in Sjögren’s Syndrome. MRI is the best diagnostic tool for detecting the findings of cerebral vasculitis and nonspecific, T2-weighted hyperintensities affecting subcortical and periventricular white matter are the most common finding. In the current report, we present MRI findings of unilateral fronto-parietal cortical atrophy, a rare finding in a case with long-standing Sjögren's syndrome.