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Scholars Journal of Medical Case Reports | Volume-6 | Issue-07
Langerhans’ Cell Histiocytosis of the Spine: Report of a Case Follow-upped for 15 years with symptomatic recurrence and Review of the Literature
Yangliang Huang, Houqing Long
Published: July 30, 2018 |
144
156
DOI: 10.36347/sjmcr.2018.v06i07.006
Pages: 462-465
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Abstract
Langerhans’ cell histiocytosis (LCH) is a benign bone lesion, it is now recognized as a pathologic entity distinguished by a clonal proliferation and accumulation of a specific histiocyte: the Langerhans’ cell. LCH can involve any bone in the body, Spinal involvement accounts for 6.5% to 25% of all skeletal LCH cases. LCH is rare in clinical practice, and a single case follow-upped for 15 years has not been reported before. We report a 17-year-old man complained of persistent thoracic pain for 2 months. He was diagnosed of LCH of thoracic spine. 15 years later the lumbar spine was involved. Pre-operative CT scans demonstrated a lesion in the first lumbar vertebral body. After 3 months observation, the pain deteriorated with instability. A gross resection with internal fixation was applied and complete pain relief without any complication was experienced.