DOI: 10.21276/sajp.2019.8.4.7

Pages: 145-155

Background & Objectives: During treatment of Multi Drug Resistance Tuberculosis, patients suffer from many adverse effects. For management of adverse effects, ancillary medications are suggested. Severe adverse effect may lead to refusal and discontinuation of treatment. Poor management of adverse effects increases the risk of default or irregular or short duration adherence to treatment and results in permanent morbidity or death. Though national TB control programmes are generally well structured, they do not collect information on adverse effects and their management directly. In this regard, pharmacovigilance should be an integral component for TB control programme. So this study had been designed to observe the clinical management of adverse effects of MDR-TB drugs in Bangladesh with objective to provide information for subjects, health workers, doctors, people and organizations concerned with the activities for prevention, control and management of MDR-TB. Methods: This observational and descriptive type of longitudinal study was carried out at the in-patient department of the National Institute for Diseases of the Chest & Hospital, Dhaka, Bangladesh. The total number of subjects included was 64.The data collection was carried out with pretested questionnaire. After the interview at the initial stage, the respondents had to take part in interview again at one month interval up to the end of 3rd month of treatment. The collected data was analyzed in terms of descriptive method.