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Scholars Journal of Medical Case Reports | Volume-6 | Issue-08
Pregnancy with Immune Thrombocytopenic Purpura and Neonatal Alloimmune Thrombocytopenia – Case Report
Pragati Aggarwal, Naimaa K Chaudhary
Published: Aug. 30, 2018 | 253 166
DOI: 10.36347/sjmcr.2018.v06i08.006
Pages: 515-517
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Abstract
Immune thrombocytopenic purpura (ITP) is a diagnosis of exclusion. It is an autoimmune disorder caused by development of IgG autoantibodies, directed against number of platelet glycoproteins. A 28 years, primigravida, booked, admitted at St Stephens Hospital at 36 weeks of gestation with intrahepatic cholestasis, false labour pains and symptomatic severe thrombocytopenia with platelet count of 10,000/mm3. She was treated with oral steroids and platelet transfusion after admission. Patient was induced at 37+2 weeks. She delivered a healthy baby girl of weight 2.88kg vaginally. Baby showed neonatal alloimmune thrombocytopenia at day 4, which was treated with intravenous immunoglobulins (IVIg). Both mother and baby were discharged with good increment in the platelet count. The aim is to clarify; when thrombocytopenia in pregnancy is clinically important, to provide guidance regarding diagnosis, management options and information about potential risks to the mother and the fetus.