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Scholars Journal of Medical Case Reports | Volume-6 | Issue-08
Persistent Parvovirus B19 Encephalitis in a Paediatric Patient with B- Lymphoblastic Lymphoma
Prasanth VR, Manjusha Nair, Priyakumari T
Published: Aug. 30, 2018 | 125 131
DOI: 10.36347/sjmcr.2018.v06i08.015
Pages: 545-547
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Abstract
Parvovirus B19 is a small single-stranded DNA virus of the Parvoviridae family. Depending on host factors, it may produce a wide array of clinical disease states. Immunocompromised patients are generally affected more severely but rarely develop prolonged and persistent infections and can be life threatening. Acute Lymphoblastic Leukemia [ALL] is associated with significant immunocompromised state that can lead to reactivation of Parvovirus B19 infection and can be life threatening. Here, we describe a child who developed persistent fatal parvovirus infection in central nervous system during treatment for B- lymphoblastic lymphoma.