DOI: 10.36347/sjmcr.2018.v06i08.024

Pages: 578-580

To report a serie of 4 patients of Acrodermatitis enteropathica which refers to a rare autosomal recessive disorder caused by hereditary and acquired defiency. 4 infants aged between the ages of 4 and 11 Months (a girl and 3 boys) presented around the age of 3 months an erythematous, vesicular and erosive lesions localized mainly on acral and perioral and periorificial areas. Consanguinity was found in two patient .There was no history of prematurity. All four infants were born at full term and received exclusive breastfeeding. There was no digestive or neurological clinical manifestation. The diagnosis was confirmed by the dosage of zinc which was low in our 4 patients and by the therapeutic test of oral zinc intake, a normalized the skin lesions in a few days was achieved. No clinical relapse was observed after oral form of zinc intake. This series reflects a rare inherited condition, characterized by perioficial, perioral and acral dermatitis without digestive symptoms, and should promptly recognized because fatality without appropriate treatment is probable.