DOI: 10.36347/sjmcr.2018.v06i08.032

Pages: 606-608

Hydatidiform mole is characterized by the abnormal fetoplacental development and trophoblastic hyperplasia which results from genetically abnormal conception because of excessive paternally derived genetic material. Molar pregnancies are associated with potentially life-threatening complications such as heavy vaginal bleeding, preeclampsia, preterm labour and thyroid abnormalities, making management of these conditions more challenging. It is classified into complete mole when there is total replacement of normal placenta by grossly dilated and hydropic villi in the absence of foetus and the incomplete or partial mole showing partial replacement with hydropic villi and visible abnormal fetal parts leading to termination of the pregnancy in first trimester. Fetus in such cases is rarely alive at the time of diagnosis and often shows gross congenital anomalies associated with triploidy and frequently have a grave prognosis owing to limited functional placental circulation and severe intrauterine fetal growth retardation.