DOI: 10.36347/sjmcr.2018.v06i10.010

Pages: 769-774

CMV infection is the main viral fetal infection responsible for congenital neurological and sensory deficit, causing deafness and delayed acquisition. Primary infection during pregnancy is the main cause of sequelae compared to secondary infections. Neonates are asymptomatic in 85% of cases, severe lesions can be seen from birth and can cause neonatal mortality in 30% of cases. Sequelae can be seen in asymptomatic newborns even late after birth. The occurrence of a CMV infection during pregnancy requires specific management to make the diagnosis and establish a prognosis. Diagnostic management of CMV infection during pregnancy relies mainly on ultrasound and fetal brain MRI, which can be supplemented by an invasive gesture and amniocentesis that confirms fetal infection. A fetal blood puncture may also be proposed as part of the prognostic evaluation. A multidisciplinary discussion in prenatal diagnosis is necessary for the study of all cases of CMV infection during pregnancy. We report here the case of congenital CMV infection discovered at 25 WA with continuation of pregnancy until the end of pregnancy and the postnatal care. Our study allows us to analyze the evolution of the case including neonatal ultrasound aspects along the pregnancy in the absence of IMG proposal. We then carry out a review of the epidemiological literature, means of diagnosis and management.