DOI: 10.36347/sjams.2023.v11i05.014

Pages: 893-899

Background: Liver is the site of many diseases, many of which become symptomatic while some are diagnosed only on autopsy. Involvement of liver is secondary to cardiac, metabolic, social problem like alcoholism, drug toxicity, herbal remedies and environmental exposures. Objectives: This study aims at finding the frequency of steatosis and steatohepatitis in autopsy specimens of liver. Methods: This was a descriptive cross-sectional study carried out at the Department of Pathology, Dhaka Medical College, Dhaka over a period of 2011-2012. Liver samples of postmortem cases from the Department of Forensic Medicine, Dhaka Medical College and autopsy samples of liver received at the Department of Pathology, Dhaka Medical College, sent from different parts of Bangladesh via postal service for histopathological examination were included in this study. Result: Satisfactory liver tissue samples for histological evaluation were available in 200 autopsy specimens (155 male and 45 female) with a mean age of 39.50±14.76 years. Out of 200 cases, the most common lesion was steatosis in 35(17.50%) cases. Steatosis mild, moderate and severe were found in 20(10%) cases, 9(4.50%) cases and 6(3.0%) cases respectively. Steatohepatitis was found in 16(8.0%) cases. Steatohepatitis with fibrous portal expansion, steatohepatitis with bridging fibrosis and steatohepatitis with cirrhosis were detected in 7(3.5%), 6(3%) and 3(1.5%) cases respectively. Conclusion: A high prevalence of steatosis and steatohepatitis was detected in postmortem liver samples of Bangladesh. Since both diseases can have serious clinical consequences, they should be considered as an important threat to the health of the general population of our country.