DOI: 10.36347/sjmcr.2018.v06i12.024

Pages: 1084-1086

Amyloidosis forms a group of disorders characterised by extracellular tissue accumulation of amorphous hyaline material. Amyloidosis in head and neck is a rare benign disease. Among the sites in head and neck, larynx is the most commonly involved. Laryngeal involvement in amyloidosis is rare and accounts for less than 1% of all benign tumors. It usually occurs in the 40 to 60 years age. It is essential to differentiate a primary laryngeal amyloidosis from malignancy for the management of the disease. A 65years old man presented to the Department of ENT with chief complaints of hoarseness of voice for the past 3 years, it is insidious in onset, gradually progressive, associated with mild dyspnoea. On Laryngoscopic examination, a pinkish white mass of size 2x1cm in supraglottic region over false vocal cords (ventricular folds) almost covering 2/3rd of the true vocal cords and anterior commissure was noted. Bilateral vocal cords mobile and bilateral aryepiglottic folds and arytenoid cartilages are normal. Patient is known smoker, all routine investigations are within normal range, and systemic diseases are ruled out. Micro laryngeal surgery done, mass excised and sent for histopathological examination, a provisional diagnosis of laryngeal amyloidosis was given. Follow up of the patient also did not show manifestation of any systemic pathology, consequently diagnosis of localized laryngeal amyloidosis was given.