DOI: 10.21276/sajp.2019.8.7.1

Pages: 313-326

This review paper focuses on the biomarkers available for the early diagnosis and investigation in the field of Osteoarthritis. The main aim is to bring out the potential approach in using the herbal medicinal plants in the treatment of osteoarthritis. Considering the adverse effects of synthetic drugs, the western world is looking for natural remedies which are safe and effective. It is also documented that, about 80% of the world’s population has a belief in traditional medicine, particularly plant drugs for their primary treatment. Medicinal plants have been known for a golden age and are highly esteemed all over the world as a rich source of therapeutic agents for the prevention of diseases and ailments. Nature has met our nation with a tremendous abundance of restorative plants. OA is a long haul unending sickness described by the degeneration of the cartilage in joints which results in bones scouring together and making solidness, torment, and weakened development. The ailment most generally influences the joints in the knees, hands, feet, and spine and is moderately regular in the shoulder and hip joints. In this way, the portrayal of potential biomarkers is imperative to guarantee their proper and ideal use. The portrayal strategy used to survey biochemical markers in OA is BIPEDS; which represents the Burden of ailment, Investigative, Prognostic, Efficacy of intercession, Diagnostic, and Safety.