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Scholars Journal of Medical Case Reports | Volume-7 | Issue-02
Metformin Induced Fixed Drug Reaction
SP Mittal,Kiranjeet Kaur, Navpreet Kaur
Published: Feb. 22, 2019 |
178
193
DOI: 10.36347/sjmcr.2019.v07i02.011
Pages: 140-142
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Abstract
It is to report a rare case of fixed drug reaction (FDR) due to metformin. Young male recently diagnosed as a case of diabetes mellitus (DM) developed FDR as discoid brownish non itchy rash over hands on next day of metformin 1000 mg (Exernmet SR) initiation. The medicine (metformin) was stopped. He was given glimpride 1mg BD initially and later on added Teneligliptin 20 mg once a day. His FDR lesions have subsided considerably. When some other physician prescribed Zetin plus (Teneglyptin 20 mg plus metformin 1000 mg), same type of lesions appeared at the same areas over hands. Because of rarity, and probably the first case in India, we report patient with FDR upon initiation and rechallenge with metformin.