DOI: 10.36347/sjmcr.2019.v07i03.009

Pages: 199-201

Ulcerative colitis is a chronic inflammatory disease that affects the colon and rectum, the pathogenesis is complex. Extra-intestinal manifestation is present in 40% of patients with ulcerative colitis. The neurological involvement is part of the extra-intestinal manifestations. We report the case of a young patient of 29 years, followed for 5 months for ulcerative colitis, placed on azathioprin. Admitted with tetraparesis rapidly ascending, associated with hypoesthesia without any sphincter disorders, evolving. Guillain-Barré syndrome was confirmed based on the results of EMG and the study of cerebrospinal fluid and after elimination of other etiologies. The decision was to treat the patient with intravenous corticosteroid therapy and discuss the infusion of immunoglobulins but the patient died on day 1 of treatment because of cardiopulmonary arrest. Guillain-barré syndrome is an unknown and rare complication of ulcerative colitis even in the case of clinical remission of ulcerative colitis. This is a serious complication that is life-threatening. It is imperative to realize an EMG and the LCR study in front of any sign of appeal.