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Scholars Journal of Medical Case Reports | Volume-7 | Issue-04
Lenalidomide Treatment in Myelodysplastic/ Myeloproliferative Neoplasms: A Case Report and Review of the Literature
Lina El Mekkoudi, El Mehdi Mahtat, Fatima Boukhchach, Kamal Doghmi, Mohammed Mikdame
Published: April 30, 2019 | 152 159
DOI: 10.36347/sjmcr.2019.v07i04.004
Pages: 280-283
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Abstract
Myelodysplastic/ myeloproliferative neoplasm with ring sideroblasts and thrombocytosis is a rare overlap syndrome, no formal guidelines for the management of this disease exist. We report the case of a 64 years old male patient who was admitted for myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis with mutation in the Janus Kinase 2 gene and hyperdiploid clone. Lenalidomide given for a period of 6 months performed to maintain a normal blood platelet count with, for the first time, sustained platelet response 24 months after discontinuation of treatment.