DOI: 10.36347/sjmcr.2019.v07i08.011

Pages: 500-502

Gall bladder carcinoma is the most common malignancy of the extrahepatic biliary tract and stands fourth amongst the gastrointestinal cancers. Mixed adenoneuroendocrine carcinoma (MANEC), a rare entity was described and recognized by WHO in 2010. It is a rare gastrointestinal neoplasm which is characterized by the presence of at least 30% each of epithelial and neuroendocrine components. MANEC of gall bladder are exceptionally rare. There is a lack of any specific radiologic or symptomatic predictors of the tumor, and so the diagnosis is made based on the histopathological findings. We have reported a rare case of MANEC of gall bladder in a 37 year old female patient who presented with obstructive jaundice and vomiting. They have an aggressive behavior and poor prognosis. Radical surgery with adjuvant chemotherapy remains the mainstay of treatment in such cases.