DOI: 10.36347/sjmcr.2019.v07i08.022

Pages: 531-533

Kimura disease is a rare form of chronic inflammatory disorder involving subcutaneous tissue, predominantly in the head and neck region and frequently associated with regional lymphadenopathy. The etiology of Kimura disease is still unknown but may be due to impairment of immune system. Kimura disease should be suspected when the clinical finding of painless unilateral cervical adenopathy and hypereosinophilia presented. Definitive diagnosis arise by histopathology examination, with hematoxylin-eosin staining showed follicular hyperplasia with perifollicular fibrosis, dense eosinophil infiltrate, and proliferation of capillary vessel lined by normal, flat, spindle-shaped endothelial cells. We reported A 37 years old man with history of soft tissue tumor on facialis dextra region, lymphadenopathy colli dextra, and exopthalmic bulbus oculi dextra over the last 10 years. Laboratory assessment on hematologic review showed that eosinophil 47.9 (10^3/ul).