DOI: 10.36347/sasjs.2023.v09i05.022

Pages: 447-449

Summary: Repeated spontaneous miscarriages are defined as at least three consecutive episodes of spontaneous miscarriage, less than 14 weeks of amenorrhea, with the same partner, in a patient under 40 years of age. 80% of these patients have an identifiable cause justifying an etiological approach. A guided history and clinical examination are necessary. An etiological assessment is to be carried out: a pelvic ultrasound and a hormonal assessment in the woman, as well as a karyotype of the two members of the couple. The other examinations are requested as a second intention. The main causes are balanced chromosomal abnormalities of the parents, sperm DNA fragmentation, congenital malformations and lesions of the uterine cavity, anti-phospholipid syndrome, unbalanced diabetes, dysthyroidism and luteal insufficiency. In the event of an identified cause, certain therapeutic or preventive measures must be discussed in order to limit the risk of recurrence.