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Scholars Journal of Applied Medical Sciences | Volume-11 | Issue-05
Demographic & Clinical Profile Analysis of Acute Viral Hepatitis E Patients in Bangladesh: A Single-Center Study
Dr. Mohammed Shafiqul Islam Bhuiyan, Dr. Md. Shahidur Rahman, Dr. Mohammad Sofiul Kadir, Dr. Mohammad Jakir Hossain, Dr. Mohammad Abu Faisal, Md. Rafiqul Islam, Dr. Jannatul Ferdous Suma
Published: May 24, 2023 | 79 68
DOI: 10.36347/sjams.2023.v11i05.022
Pages: 941-945
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Abstract
Background: In Bangladesh, Acute hepatitis is seen sporadically round the year. On the other the other hand, the incidence of acute viral hepatitis E increases after floods as this allows sewerage contamination of piped and groundwater. Objective: In this study our main goal is to evaluate the demographic & Clinical Profile Analysis of Acute Viral Hepatitis E Patients in Bangladesh. Method: This prospective observational study was conducted in the Department of Gastroenterology, US-Bangla Medical College & Hospital during the period from July 2018 to June 2019, in Bangladesh. A total of 35 patients who were attending the Hepatology unit with acute viral hepatitis were included as the study population for this study. By enzyme-linked immunosorbent assay, all viral markers were tested. Results: Majority, 34.4% belong to 21-30 year’s age group, and 81.3% were male. Positive cases of Anti HAV IgM were 10% followed by Anti HEV IgM seen in 100%, however, none of the Anti HCV IgM seen in patients. Higher serum bilirubin was 8.82±5.65. Followed by Levels of aspartate aminotransferase (AST) was 1141.00±128.69, S.GPT ALT was 1380.75±751.28, S. Creatinine was10.00±18.33. Moreover, Prothrombin Time was seen longer in patients. Which means patient’s needs higher blood clotting time than usual. Conclusion: Acute viral hepatitis E is the leading cause of wide spectrum of liver disease in young male adults ranging from severe acute viral hepatitis, to decompensation of liver in cirrhotic in Bangladesh.