DOI: 10.36347/sjams.2023.v11i05.024

Pages: 953-958

Introduction: Urinary tract infections are a public health problem due to the excess mortality and the additional costs they entail. Objective: To monitor the evolution of antibiotic resistance of uropathogenic germs over the last three years in patients treated at the CHU Med VI of MARRAKECH. Materials and Methods: Descriptive study carried out over a period of 3 years (from January 2018 to December 2020) including all urinary tract infections retained as meeting the criteria for microbiological and clinical infections in patients treated at the Mohammed VI University Hospital in Marrakech. Results: Out of a total of 37,394 ECBUs, the prevalence of UTI was 11% (n = 4275). The average age was 36 years, with a standard deviation of 25.9 years. The sex ratio M / F was 0.95. Uropathogenic germs were represented mainly by Enterobacteriaceae 78%. E. coli accounted for 66%. Enterobacteriaceae were resistant to third generation cephalosporins in 22% of cases, decreased sensitivity to Carbapenems in 7.2%, resistant to ciprofloxacin in 31%, to Cotrimoxazole in 42%, to Gentamicin in 17.5%, to Amikacin in 2%. Extended spectrum beta-lactamase production was 21%. Over the past three years, 895 multi-resistant bacteria have been identified, i.e. 23%. Klebsiella spp accounted for 41%. Conclusion: The results testify to the increased resistance of uropathogenic bacteria. Updated local studies are important to understand the state of play of bacterial ecology and resistance profiles in order to avoid treatment failures.