DOI: 10.36347/sasjm.2023.v09i06.006

Pages: 598-600

Blood transfusion is a therapeutic act that consists in administering blood or one of its cellular or plasma components, from one or more healthy subjects called "donors" to a sick subject called "recipient”. Blood safety is ensured by controlling all stages of the transfusion chain, from blood collection, preparation and biological qualification to the performance of the transfusion act and even the follow-up of the recipients. The basis of immuno-hematological safety is the compatibility between the erythrocyte characteristics of the donor and those of the recipient. From an immuno-hematological point of view, all the antigens present on the surface of an individual's red blood cells determine the erythrocyte phenotype. Only a limited number of erythrocyte antigens that make up this erythrocyte phenotype are sought in current practice. Only a perfect knowledge of the phenotypic and molecular immune-hematological data of donors and recipients will allow to determine the true perimeter of transfusion safety. On this basis, our work focuses on the feasibility of immune-hematological examinations in blood transfusion.