DOI: 10.36347/sasjm.2023.v09i06.015

Pages: 635-640

Malignant lymphomas constitute a very heterogeneous group of malignant proliferation of lymphoid tissue whose starting point is extramedullary. The confirmatory diagnosis is based on the anatomopathologic examination of the surgical specimen. Immunohistochemical typing is used to determine Hodgkin's Lymphoma (HL) and other non-Hodgkin's lymphomas (NHL). The treatment of these lymphomas involves a multidisciplinary approach and includes surgical excision, cryotherapy, chemotherapy which can be associated with radiotherapy. Very few studies carried out on orbital lymphomas in Sikasso. The purpose of our study was to write the diagnostic procedures in a secondary center and the management as well as the prognosis. It was a 23-year-old young woman with no particular history, no notion of taking stimulants, who consulted for a necrotizing and painful swelling of the right eye evolving for more than 1 year in a progressive manner despite corticosteroid therapy. Imaging and pathological examination of the surgical specimen led to the diagnosis of large cell lymphoma. Surgical excision was the therapeutic means performed. The postoperative course was good with healing of the wound after 2 months. After 3 months of follow-up, the patient would have died after a period of loss of sight. The clinical polymorphism of lymphomas can mask the diagnosis and delay the therapeutic management which determines the prognosis.