DOI: 10.36347/sajp.2020.v09i01.001

Pages: 1-4

The present study was designated for the evaluation of the anti-inflammatory activity of four essential oils (Aucoumea klaineana Pierre, Canarium schweinfurthii Engl., Dacryodes buettneri HJ Lam, Dacryodes edulis (G. Don) HJ Lam) derived from medicinal plants from Gabon using the in vitro model. The anti-inflammatory activity of essential oils was determined using the method of denaturing the proteins of egg albumin. Essential oil of Aucoumea klaineana (IC50 = 1.11 ± 0.02 µg / mL) showed better thermal anti-denaturation efficacy of ovalbumin, followed by Dacryodes buettneri (IC50 = 02.95 ± 0.69 µg / mL) and Dacryodes edulis (IC50 = 09.32 ± 1.58 µg / mL). Canarium schweinfurthii essential oil (IC50 = 13.51 ± 1.34 µg / mL) exhibited weak activity compared to other essential oils, however, its inhibitory action is more effective than Diclofenac sodium (IC50 = 22.39 ± 1.04 µg / mL). This study supports the traditional use of these plants to treat certain disorders linked to inflammation.