DOI: 10.36347/sasjm.2023.v09i06.019

Pages: 655-658

Vitamin B12 or cobalamin is a micronutrient found mainly in dairy and meat products. It is essential in the synthesis of DNA and RNA. In infants, hypovitaminosis B12 often causes neurological and hematological signs, and skin changes such as melanoderma are an uncommon manifestation. Blood count may not show anemia or macrocytosis, and decreased serum vitamin B12 associated with methylmalonic aciduria or total homocysteine levels confirm the diagnosis. Etiological assessment should also concern the mother. Early replacement treatment with vitamin B12 is the cornerstone of management. We report the case of B12 hypovitaminosis revealed by a delay in psychomotor milestones and stunted growth in height and weight associated with melanoderma, without anemia or macrocytosis on the blood count.