DOI: 10.36347/sajp.2020.v09i01.007

Pages: 32-35

Chronic kidney disease (CKD) increased and became a public health problem. Patients who have end stage renal disease (ESRD) and who receive hemodialysis (HD) are expected to be given 10 to 12 medications daily and many of these medications need multiple doses per day. Owing to poly-pharmacy, recurrent medication modifications on HD versus non- dialysis days, therapeutically unstable nature of the illness and limited life styles, these patients is at high risk for having drug related problems (DRPs).This study was conducted to evaluate potential DDIs among HD patients.An observational- retrospective study was carried out; it included ESRD patients undergoing maintenance hemodialysis in the HD unit in the King Hussein Medical Centre (KHMC) at the Royal Medical Services (RMS) in Jordan/Amman. The study included 300 patients, a total of 930 potential interactions were identified in 277 (92.3 %) patients. Patients were prescribed 8–12 drugs with a mean (± SD) of 8.26 ± 3.56.