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Scholars Academic Journal of Pharmacy | Volume-9 | Issue-01
The Efficacy of Bupivacaine vs Bupivacaine with Dexamethasone for Supraclavicular Brachial Plexus Block in Patients Undergoing UpperLimb Surgeries
Khalid Ali Khaleel, Zaid Al-Attar
Published: Jan. 30, 2020 |
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DOI: 10.36347/sajp.2020.v09i01.009
Pages: 46-50
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Abstract
Objective: Brachial plexus block using bupivacaine as compared to general anesthesia is regarded as a valuable
alternative as it induces adequate muscle relaxation, excellent analgesia intra and post operatively. Dexamethasone
was combined with bupivacaine to study its effects in terms of onset and duration of sensory and motor block after
their administration in patients undergoing upper limb surgeries by implementing the supraclavicular block. Materials
and methods: Brachial plexus block is a viable alternative to general anesthesia as it provides adequate muscle
relaxation, excellent intraoperative and post-operative analgesia. Dexamethasone, a synthetic glucocorticoid was
combined with local anesthetics to study the effects. This study was conducted to compare the onset and duration of
sensory and motor block following administration of either bupivacaine and bupivacaine‑ Dexamethasone in patients
undergoing upper limb surgeries under USG guided supraclavicular block. Materials and methods: 100 ASA II, III,
IV patients between of 18 and 79 years who underwent elective upper limb surgeries randomly allocated into two
groups of 50 each by a sealed envelope technique to receive 20 ml of 0.5% Bupivacaine and 2 ml of normal saline in
Group BS and 20 ml of 0.5% Bupivacaine with 2ml (8mg) of Dexamethasone in Group BD. The onset and duration of
sensory and motor blockade were observed between the two groups in addition to analgesic effect duration. Results:
The onset of sensory and motor blockade was faster in Group BD when compared to Group BS (p<0.0001). The
duration of sensory and motor blockade was longer in Group BD when compared to Group BS (p<0.0001). There were
no significant hemodynamic changes in the study group. Conclusion: Dexamethasone when added to Bupivacaine in
supraclavicular block shortens the onset time and prolongs the duration of sensory and motor blockade without any
systemic side effects.