DOI: 10.36347/sajb.2016.v04i03.023

Pages: 283-287

Chronic renal failure (CRF) is a worldwide health problem, a leading cause of mortality in the developed countries. Patients with CRF are at higher risk for cardiovascular disease (CVD). Hyperkalemia is a commonly encountered problem in patients with end- stage renal disease(ESRD). The aim of the present study is to assess the effect of Hemodialysis (HD) on serum electrolytes, which compared with healthy controls and also correlation of serum electrolyte levels before and after hemodialysis was assessed. 40 hemodialysis patients with ESRD were tested to assess their serum electrolytes, Blood urea and Serum Creatinine before and after haemodialysis (HD).Serum electrolytes was estimated by electrolyte kit method, Serum Creatinine was estimated by jaffs method and Blood urea was estimated by Diacetylmonoxime (DAM) method by using semi-auto Analyzer in Biochemistry Department. There was a significant effect of Hemodialysis on serum electrolytes particularly serum potassium levels. The pre-Hemodialysis K+ was 5.25 ±0.72 mmol/L and post-hemodialysis K+ was 3.8±0.36 mmol/L (P<0.0001 ESS).The pre-hemodialysis Na+ was 134.5±2.6 and post - hemodialysis Na+ was136.6 ±5.8 (P = 0.0399 SS). The pre-hemodialysis Cl- was 102.2 ± 2.29 and post-hemodialysis Cl- was 101.3 ± 1.92 (P 0.0605 NS).We conclude that serum potassium was significantly decreased in post-hemodialysis states compared with pre-hemodialysis levels. Although serum sodium, serum chloride levels not significantly affected after hemodialysis. Post-hemodialysis serum potassium decrement(<3.5mmol/L) may have an arrhythmogenic potential and Hemodialysis is a prefer technique to correct biochemical abnormalities in ESRD patients