DOI: 10.36347/sjams.2017.v05i12.038

Pages: 4979-4984

Buprenorphine or dexmedetomidine used as adjuvant with 0.5% levo bupivacaine intrathecal to prolong the duration of analgesia. Eighty patients were randomly allocated to two groups, Group B received 60μg of buprenorphine with 15mg of 0.5% levo-bupivacaine and Group D received 5μg of dexmedetomidine with 15mg of 0.5% levo-bupivacaine. The onset and duration of sensory and motor blockade, the sensory and motor regression times, Ramsay sedation score in post-operative period were recorded. Hemodynamic changes and time to use first rescue analgesia were also recorded. There was no significant difference in the onset time of sensory block and motor block in group B and group D. Duration of analgesia was in Groups D and group B was 495.42±24.95 min. v/s 292.22±24.94 min. respectively, with p value<0.0001. The Duration of motor block was 416.67±28.22 min in group D, as compared to 205.45 ± 13.14 min in group B. Ramsay sedation score at the end of surgery was 3.82 ±0.67 in group D as compared to 2.07 ± 0.26 in group B. The time to give first rescue analgesia was significantly prolonged in Group D compared with Group B. Dexmedetomidine produces a prolongation in the duration of the motor and sensory block and postoperative analgesia when compared to buprenorphine with preserved hemodynamic stability.